OPERA(_Optimizing _Patient _Experience and _Response to Topical _Analgesics)
OPERA is our closed, PAIN Study. This IRB-approved clinical observational study focused on reducing pain with topical/transdermal analgesics for patients with chronic neuropathic or musculoskeletal pain.
As seen in the Journal of Pain, OPERA is now a peer-reviewed published study with crucial results on alternative pain management and the fight against the opioid epidemic.
Key Interim Results
Chief Medical Officer
The Pain Center of Fairfield
Senior Attending Physician
Department of Medicine Bridgeport Hospital
Chronic Pain & Recovery Program Silver Hill Hospital
New Canaan, CT
Director, Pain and Palliative Care
Englewood Hospital and Medical Center
New York, NY
Clinical Instructor, Anesthesiology
Icahn School of Medicine at Mount Sinai
New York, NY
To evaluate patient perceptions of pain treatment with the use of topical formulations alone or in combination with neuropathic supplements via a patient-reported survey.
OPERA study participants using a topical analgesic formulation for pain are reporting positive results. Statistically significant and positive interim OPERA results continue to be presented at important conferences, including the 4th Annual International Conference on Opioids at Harvard Medical School, among others.
Reduced pain severity for patients with neuropathic and musculoskeletal pain
Reduced pain interference with general activity, mood, sleep, and life enjoyment
Reduced number of primary pain complaints for arthritis, neuropathy, or radiculopathy
Reduced use of over-the-counter medications, anti-inflammatory medications, and opioid analgesics
95% of patients were satisfied with the topical analgesic, and the topical analgesics were safe and well-tolerated.